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目的探讨前路一期病灶清除植骨内固定治疗胸腰椎结核的临床疗效。方法对31例胸腰椎结核患者在常规抗结核药物治疗的基础上,采取前路病灶清除、一期自体骨或人工骨植骨及内固定,术后继续抗结核药物治疗12~18个月。结果全组31例均治愈,无组织器官损伤、切口感染等并发症发生。平均随访时间为15个月,患者植骨融合满意,内固定牢靠,术后脊柱后凸Cobb角平均矫正13.4°,15个月植骨愈合率100%,随访期间无结核复发及窦道形成。结论前路一期病灶清除植骨内固定治疗胸腰椎结核具有后凸畸形矫正良好、重建脊柱稳定性好、可早期活动、术后并发症少等优点,可作为胸腰椎结核安全有效的治疗术式。
Objective To investigate the clinical effect of anterior debridement and bone graft in the treatment of thoracolumbar tuberculosis. Methods Thirty - one patients with thoracolumbar vertebral tuberculosis were treated with conventional antituberculous drugs, followed by anterior debridement, one - stage autologous or artificial bone graft and internal fixation, and continued anti - TB drug therapy for 12 to 18 months after operation. Results The whole group of 31 cases were cured, no tissue and organ damage, incision infection and other complications. The average follow-up time was 15 months. The patients had satisfactory fusion and internal fixation. The average Cobb angle of post-operative kyphosis was 13.4 °. The healing rate of bone graft at 15 months was 100%. No recurrence of tuberculosis and sinus formation were observed during follow-up. Conclusion Anterior debridement and bone graft fixation for thoracolumbar vertebral tuberculosis has the advantages of good kyphosis correction, good reconstruction of spinal column, early activity and few postoperative complications, which can be used as a safe and effective treatment for thoracolumbar tuberculosis formula.