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本文报道3例身高矮缩的病人,2例接受血液透析10年以上,第3例为老人。3例均经骨组织定量测定证实为晚期甲状旁腺功能亢进症(甲旁亢)。例1男性,44岁。透析10年余,有驼背,2年来矮缩了9cm,血钙1.77~2.10mmol/L,血磷1.47~2.29mmol/L,碱性磷酸酶(AKP)16~20U。手部 X 线片正常,脊柱 X 线片有轻度弥漫脱钙并有早期双凹陷。髂骨活检为甲旁亢。血甲状旁腺素(PTH)升高为5.14ng/ml(正常<1.0ng/ml),血25羟胆骨化醇(25OHD)正常,行甲状旁腺次全切除术,切除了260mg 增生的甲状旁腺。例2男性,56岁。血液透析11年,身高矮缩8.5cm,手 X 线片正常,脊柱X 线片示胸椎明显后突,并有明显弥漫脱钙,血钙2.45~2.50mmol/L,血磷2.3~2.8mmol/L,AKP16~23 U,髂骨活检显示严重的甲旁亢。行甲状旁腺次全切除术,切除增生的甲状旁腺1.1g。例3男性,73岁,病人几个月来身高矮缩,并有驼背,经测量指
This article reports 3 patients with shortening height, 2 patients undergoing hemodialysis more than 10 years, the third case of the elderly. Three cases were confirmed by bone tissue quantitative determination of advanced hyperparathyroidism (hyperparathyroidism). Example 1 Male, 44 years old. Dialysis more than 10 years, a humpback, 2 years dwarfing 9cm, calcium 1.77 ~ 2.10mmol / L, phosphorus 1.47 ~ 2.29mmol / L, alkaline phosphatase (AKP) 16 ~ 20U. Normal hand X-ray, spine X-ray mild diffuse decalcification and early double depression. The iliac biopsy is hyperparathyroidism. Blood parathyroid hormone (PTH) increased to 5.14ng / ml (normal <1.0ng / ml), blood 25 hydroxycholecalciferol (25OHD) normal, subtotal parathyroidectomy, removal of 260mg hyperplastic Parathyroid. Example 2 male, 56 years old. Hemodialysis 11 years, height and shortening 8.5cm, normal hand X-ray, X-ray showed thoracic obvious after sudden, and significant diffuse decalcification, calcium 2.45 ~ 2.50mmol / L, phosphorus 2.3 ~ 2.8mmol / L, AKP16 ~ 23 U, iliac biopsy showed severe hyperparathyroidism. Subtotal parathyroidectomy, removal of hyperplastic parathyroid 1.1g. Example 3 Male, 73 years old, the patient was shortened for several months and had a hump, measured by the measure