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目的分析某院药品不良反应发生的原因及特点,为临床合理用药以及药物安全性评价提供依据,促进合理用药。方法收集该院上报279例ADR报告进行回顾性分析。结果 279例ADR报告中,各年龄段均有分布;给药途径以静脉滴注为主,250例,占89.61%;引起ADR最常见的药物为抗感染药物,共185例(61.67%);以皮肤及附件损害为主,占37.28%。结论药品不良反应的发生与多种因素有关,应加强ADR的监测。
Objective To analyze the causes and characteristics of adverse drug reactions in a hospital and provide the basis for clinical rational drug use and drug safety evaluation to promote rational drug use. Methods The hospital reported 279 cases of ADR report for retrospective analysis. Results 279 cases of ADR were distributed in all age groups. The route of administration was mainly intravenous drip infusion, with 250 cases accounting for 89.61%. The most common drug causing ADR was anti-infective drug, with a total of 185 cases (61.67%). The main damage to the skin and accessories, accounting for 37.28%. Conclusion The occurrence of adverse drug reactions and many factors related to the need to strengthen the monitoring of ADR.