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目的 评估前列安栓治疗慢性前列腺炎各种疼痛和不适感等症状的有效性、安全性和依从性。 方法 安慰剂对照随机双盲试验。 72例慢性前列腺炎患者随机分为两组。治疗组 36例 ,每晚前列安栓 1粒纳肛 ,连续 1个月 ;对照组 36例 ,安慰剂治疗 1个月。根据前列腺按摩液 (EPS)和美国国立卫生院 (NIH)前列腺炎症状评分评估疗效。 结果 治疗组痊愈 1例 (2 .8% ) ,显效 7例(2 0 .0 % ) ,有效 16例 (45 .7% ) ,总显效率 2 2 .8% ,总有效率 6 8.6 %。对照组无痊愈病例 ,显效 2例(5 .7% ) ,有效 8例 (2 2 .8% ) ,总显效率 5 .7% ,总有效率 2 8.6 %。两组各有 1例在治疗 2周内退出试验。两组相比 ,总有效率和总显效率差别均有显著性意义 (P <0 .0 5 ) ;不良反应发生率差别无显著性意义 (P >0 .0 5 )。 结论 前列安栓治疗慢性前列腺炎安全、有效 ,患者依从性较好
Objective To evaluate the effectiveness, safety and compliance of Qianliean suppository in treating various symptoms of pain and discomfort in chronic prostatitis. Methods Placebo-controlled randomized double-blind trial. 72 patients with chronic prostatitis were randomly divided into two groups. In the treatment group, 36 cases were treated with Qianliean suppository once a night for 1 month continuously. In the control group, 36 cases were treated with placebo for 1 month. Efficacy was assessed according to Prostate Massage Fluid (EPS) and National Institutes of Health (NIH) prostatitis symptom scores. Results The treatment group was cured in 1 case (2.8%), markedly effective in 7 cases (20.0%), effective in 16 cases (45.7%), the total effective rate was 22.8% and the total effective rate was 8.66%. In the control group, there were no cured cases, 2 cases (5 .7%) were markedly effective and 8 cases (22.8%) were effective. The total effective rate was 5.7% and the total effective rate was 8.66%. One in each group exited the trial within two weeks of treatment. There was a significant difference between the two groups in the total effective rate and total effective rate (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Qianliean suppository in the treatment of chronic prostatitis is safe and effective, and the patient compliance is better