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目的:研究急性脑梗死患者脑磁图(magnetoencephalography,MEG)体感诱发磁场发生源等价电流偶极子(equivalentcurrentdipole,ECD)强度变化特征。方法:对15例急性脑梗死患者于发病后3～4周进行体感诱发磁场(SEFS)检测;同时检测16例健康志愿者作为对照。电刺激部位为腕部正中神经处,电流脉冲宽度0.3ms,刺激间隔0.5s。SEFS波峰由ECD评估。结果:所有受检者SEFs的最基本波形为M20,急性脑梗死患者患侧ECD强度减小(P<0.01)。结论:MEG可灵敏地检测出急性脑梗死患者体感皮层中枢功能损伤。
Objective: To study the characteristics of the equivalent current dipole (ECD) intensity of somatosensory evoked field in magnetoencephalography (MEG) patients with acute cerebral infarction. Methods: Fifteen patients with acute cerebral infarction were tested for somatosensory magnetic field (SEFS) 3 to 4 weeks after onset. Sixteen healthy volunteers were also used as controls. The site of electrical stimulation is the median nerve of the wrist. The current pulse width is 0.3ms and the stimulation interval is 0.5s. The SEFS peak is evaluated by the ECD. Results: The most basic waveform of SEFs in all subjects was M20, and the intensity of ipsilateral ECD in patients with acute cerebral infarction was decreased (P <0.01). Conclusion: MEG can sensitively detect central nervous system dysfunction in patients with acute cerebral infarction.