Buecker于三十多年前发现一种体液性的神经生长因子(NGF)开创了神经细胞生物学的新纪元。其重要性越来越受到人们的重视,是目前研究得最为深入的一个生长因子。 [来源] 神经生长因子来源甚为广泛。起初在新生小鼠的肉瘤中发现,后来在成年小鼠的多种器官,如颌下腺、甲状腺、肾脏、心脏和随意肌中也发现有此种因子存在。其中以颌下腺含量最高;此外,在蛇毒中亦发现,而且含量很高。 Buecker discovered a body fluid nerve growth factor (NGF) more than thirty years ago that pioneered a new era in neurobiology. Its importance has drawn more and more attention from people and is the most researched one growth factor at present. [Source] NGF is a very popular source. Originally found in sarcomas of newborn mice, later found in various organs of adult mice, such as the submandibular gland, thyroid, kidney, heart and voluntary muscles. Among them, the submandibular gland content is the highest; In addition, it is also found in snake venom, and its content is very high.