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骨碎补注射液对预防和治疗链霉素引起的急性毒副反应是一个有效的药物。本文结果指出,50％骨碎补注射液和链霉素联合应用对链霉素的LD_(50)、生物效价、体外抗菌活性和血清浓度没有显著的影响。链霉素用50％骨碎补注射液溶解后,在48小时内对链霉素溶液的pH和澄明度同样没有影响。因此,50％骨碎补注射液可以作为链霉素的溶剂和链霉索一起应用。当骨碎补注射液被单独试验时,在体外1:400的浓度具有抗结核杆菌的活性。
Drynaria Injection on the prevention and treatment of streptomycin-induced acute toxicity is an effective drug. The results of this study indicate that the combination of 50% drynaria injection and streptomycin has no significant effect on streptomycin LD 50, biological potency, in vitro antibacterial activity and serum concentration. Streptomycin with 50% Drynaria injection solution, within 48 hours on the streptomycin solution pH and clarity also had no effect. Therefore, 50% Drynaria Injection can be used as a streptomycin solvent with streptomyces. When Drynaria Injection is tested alone, it has anti-Mycobacterium tuberculosis activity at a concentration of 1: 400 in vitro.