自从 Shinn 于1962年发现灭滴灵的抗厌氧菌作用后,该药被广泛应用于厌氧菌感染的治疗,近年来开始应用静脉输液给药。1988年4月,我们在治疗一例腐败坏死性口底蜂窝织炎患儿,因静脉输入灭滴灵引起锥体束综合征(pyramidal tractsyndrome),报告如下。患儿刘某某,女,2岁,因高热(T39.5℃～40.2℃),颏下及双颌下区肿胀三天。临床诊断为腐败坏死性口底蜂窝织炎入院。 Since Shinn discovered the anti-anaerobic effect of metronidazole in 1962, it has been widely used in the treatment of anaerobic infections. In recent years, it has been used as an intravenous infusion. April 1988, we are in the treatment of a case of rotten necrotizing mouth cellulite in children, intravenous infusion of metronidazole caused pyramidal tract syndrome (pyramidal tractsyndrome), the report is as follows. Liu Moumou children, female, 2 years old, due to high fever (T39.5 ℃ ~ 40.2 ℃), submental and submandibular area swelling for three days. Clinical diagnosis of necrotizing venereal cellulitis hospitalized.