Ⅰ.引言甲状腺是重要的内分泌器官之一,其主要功能是分泌甲状腺激素(以后简称 TH), 藉以控制机体之代谢,甲状腺与细胞生长、成熟、分化有着密切的关系。人类的甲状腺疾病颇为常见,甲状腺瘤肿之发生亦屡见不鲜。在实验动物体内,可藉人工方法引起甲状腺瘤肿。在大白鼠中,当食料中长期的缺碘,以抗甲状腺物质(如硫脲及其衍生物、 I. INTRODUCTION The thyroid gland is one of the most important endocrine organs. Its main function is to secrete thyroid hormone (hereinafter abbreviated as TH), which controls the body’s metabolism. The thyroid gland has a close relationship with cell growth, maturation and differentiation. Thyroid diseases in humans are quite common and the occurrence of thyroid tumors is also common. In experimental animals, thyroid neoplasia can be induced by artificial methods. In rats, when the food is long-term iodine-deficient, anti-thyroid substances (such as thiourea and its derivatives,