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Thompson曾报道2,4-二氨基-6-(3,4-二氯苄基)-氨基喹唑啉PAM-1392 WR-9055(I_1)对伯氏鼠疟原虫,鸡疟原虫和食蟹猴疟原虫以及诺氏猴疟原虫均有较强的抗疟活性。并对伯氏鼠疟抗性株同样有明显作用。Peters报道PAM-1392对鼠疟原虫-斯氏按蚊系统Plas-
Thompson reported the resistance of Plasmodium berghei, Plasmodium falciparum and Cynomolgus macaques to 2,4-diamino-6- (3,4-dichlorobenzyl) -quinoquinazoline PAM-1392 WR-9055 (I_1) Protozoa and Plasmodium knowlesi have strong anti-malarial activity. And Rubescens malaria resistant strains also have a significant role. Peters reports that PAM-1392 inhibits Plasmodium and Anopheles stephensi Plas-