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青少年起病的成年型糖尿病 (ｍａｔｕｒｉｔｙ ｏｎｓｅｔｄｉａ ｂｅｔｅｓｏｆｔｈｅｙｏｕｎｇ ,ＭＯＤＹ)是一组由于多种单基因突变 ,胰腺 β细胞功能缺陷所致的特殊类型的糖尿病。其基本病理生理机制为原发性胰腺 β细胞功能缺陷而非胰岛素抵抗 (ＩＲ)。2 0世纪 5 0年代 ,
Maturity on sengel betes of the young (MODY) is a group of specific types of diabetes due to multiple single-gene mutations and pancreatic beta-cell dysfunction. Its basic pathophysiological mechanism is a primary pancreatic β-cell deficit rather than insulin resistance (IR). 1950s ,