氧氟沙星又名氟嗪酸,是第三代喹诺酮类抗菌剂,具有抗菌谱广、活性强、毒付作用低、临床疗效高 等特点。最近国外报导该类药物已突破抗菌范畴,在抗病毒、抗肿瘤方面取得新的进展。随着临床应用范围的扩大新制剂也不断研制成功。本文就氧氟沙星制剂及临床应用情况作一概述。 Ofloxacin, also known as fluorozinc acid, is the third generation quinolone antibacterial agent, with broad antibacterial spectrum, strong activity, low toxicity, clinical efficacy and higher. Recently reported that such drugs have exceeded the antimicrobial category, made new progress in anti-virus, anti-tumor. With the expansion of clinical application of new formulations have also been successfully developed. This article gives an overview of ofloxacin formulations and clinical application.