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副肌球蛋白是多数无脊椎动物肌肉中的主要结构蛋白,脊椎动物则无副肌球蛋白,若用作疫苗候选抗原将不会发生自身免疫反应。已证明曼氏血吸虫的副肌球蛋白(Sm97)有希望成为曼氏血吸虫病疫苗候选抗原,其部分及全部cDNA已得到。本文报告编码日本血吸虫副肌球蛋白的cDNA的克隆及测序。作者从日本血吸虫菲律宾株成虫
Paramyosin is the major structural protein in most invertebrate muscles and vertebrates do not have paramyosin. Autoimmune reactions do not occur if used as a vaccine candidate antigen. Paramyosin (Sm97) of Schistosoma mansoni has been shown to be a candidate antigen for the Schistosoma mansoni vaccine, some and all of which have been obtained. This article reports the cloning and sequencing of the cDNA encoding the para-myosin of Schistosoma japonicum. Author from Japan Schistosoma japonicum adult