血管生成(Angiogenesis)是指从已有的微血管床上新生出以毛细血管为主的血管系统,它是许多生理和病理过程的基本事件之一。过度的血管生成是多种慢性炎症疾病及肿瘤的标志,可致疾病进行性发展。口腔扁平苔藓(OLP)是一种病因不明的慢性炎性疾病,WHO将其列入潜在恶性病变的范畴,近来血管生成在OLP发生发展中的作用受到关注,本文就相关研究进行综述。 Angiogenesis refers to the generation of a capillaries-predominant vascular system from an existing microvasculature, which is one of the basic events of many physiological and pathological processes. Excessive angiogenesis is a hallmark of many chronic inflammatory diseases and tumors that can lead to progressive disease progression. Oral lichen planus (OLP) is a chronic inflammatory disease with unknown etiology, which is listed by WHO as a potential malignant disease. Recently, the role of angiogenesis in the development of OLP has drawn attention. This article reviews the related research.