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用反相ＨＰＬＣ法测定６名健康受试者单次口服格列吡嗪片剂５ｍｇ后的血药浓度。结果表明，口服本品的体内过程符合单室开放模型，服药后血糖水平的降低与血药浓度呈正相关。
The plasma concentrations of 5 mg glipizide tablets in 6 healthy volunteers were determined by reversed-phase HPLC. The results showed that oral administration of this product in vivo process in line with the single-compartment open model, after taking blood glucose levels decreased and plasma concentrations were positively correlated.