据冰岛deCODE genetics股份有限公司称,他们的研究人员在研究了冰岛120多个家庭的490余名高血压患者后得出结论,高血压与染色体18q连锁。该研究的研究人员通过交叉配血试验从冰岛Landspitalinn大学医院的高血压门诊挑选出高血压患者,再利用冰岛全国范围的家系数据库鉴定出所需研究的家系。然后,研究人员应用904个微卫星标记物对所有患者的基因组进行扫描,结果发现一个高血压等位基因与染色体18q连锁,LOD值为4.60。这项研究的主要负责人Kristjansson K指出,该研 According to Icelandic deCODE genetics GmbH, their researchers concluded after studying more than 490 hypertensive patients in more than 120 Icelandic families that hypertension is linked to chromosome 18q. Researchers from the Hypertensive Clinic at the Landspital University University Hospital in Iceland conducted cross-matching tests to identify hypertensive patients and used the Icelandic pedigree database to identify the pedigrees needed for the study. The researchers then scanned the genomes of all patients with 904 microsatellite markers and found that a high blood pressure allele was linked to chromosome 18q with a LOD of 4.60. Kristjansson K, principal investigator of the study, noted the research