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目的:观察急性有机磷农药中毒中间综合征的临床疗效。方法:对我院2011年02月到2012年01月收治的46例急性有机磷农药中毒中间综合征患者应用机械通气、阿托品、解磷定进行治疗,观察临床疗效。结果:本组46例急性有机磷农药中毒中间综合征患者均使用气管插管治疗,有18例实施气管切开治疗。治愈44例,死亡2例,治愈有效率为95%。呼吸机使用最短时间为3天,最长为22天。经过临床观察,恢复较早的是胆碱能神经障碍患者,最迟的是呼吸机麻痹患者。结论:对急性有机磷农药中毒中间综合征患者进行及时的机械通气,在早期治疗中应用足量阿托品和解磷定,能够提高抢救成功率。
Objective: To observe the clinical effect of acute organophosphorus pesticide poisoning intermediate syndrome. Methods: 46 cases of acute organophosphorus pesticide poisoning intermediate syndrome patients admitted to our hospital from February 2011 to January 2012 were treated with mechanical ventilation, atropine and phoxim, and the clinical effects were observed. Results: 46 cases of acute organophosphorus pesticide poisoning intermediate syndrome patients were treated with endotracheal intubation, tracheotomy in 18 cases. 44 cases were cured and 2 died, the effective rate of cure was 95%. Ventilator use the minimum time of 3 days, up to 22 days. After clinical observation, the recovery of patients with cholinergic neuropathy earlier, the latest is the ventilator paralysis patients. Conclusion: Acute mechanical ventilation in patients with acute organophosphorus pesticide poisoning syndrome in patients with timely mechanical ventilation in the early treatment of adequate atropine and phosphate solution, can improve the success rate of rescue.