报道1例因皮肤接触三氯丙烷(TCP)而致严重急性肝损伤的病例资料。入院后患者丙氨酸氨基转移酶曾升至4 320 IU/L,伴发热、尿少、腹胀、皮肤和巩膜中度黄染等表现。给予激素、保肝降酶、血液灌流等综合治疗后痊愈。本例再次提示,企业应切实做好接害工人的职业危害防护工作,避免类似事故再次发生。 One case of severe acute liver injury due to skin contact with trichloroethane (TCP) was reported. After admission, patients with alanine aminotransferase had risen to 4 320IU / L, with fever, oliguria, abdominal distension, yellowish skin and sclera and so on. Give hormones, liver enzymes, hemoperfusion and other comprehensive treatment recovered. This case once again prompts that enterprises should do a good job occupational hazards of workers exposed to work to prevent the recurrence of similar incidents.