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目的:加强临床上对黑斑息肉病是家族性疾病的认识。方法:对黑斑息肉病一家族病例临床资料进行回顾性分析。结果:家系中6例患者1例可疑者,2例行肠套叠复位加肠部分切除术;1例行小肠部分切除术;1例行小肠局部切除加直肠部分切除;1例十二指肠息肉癌变行胰十二指肠切除术,1例行内窥镜下切除术。其中2例最终死于肺癌,1例死于癌变肝转移。结论:黑斑息肉病是家族性疾病,可以癌变,并可以并发其他器官的恶性肿瘤,应行终身监测。治疗首选胃镜、肠镜下切除术,外科手术力求简洁,为术后随诊创造条件。
OBJECTIVE: To strengthen the clinical understanding of melasma polyposis as a familial disease. Methods: Retrospective analysis was performed on the clinical data of a family of cases of melasma polyposis. RESULTS: One patient was suspicious in 6 patients in the family, 2 patients underwent intussusception and partial bowel resection; 1 patient underwent partial small bowel resection; 1 patient underwent partial resection of the small intestine plus partial rectal resection; 1 patient had duodenum. Polypoid carcinoma undergoes pancreatoduodenectomy, and one case underwent endoscopic resection. Two of them died of lung cancer and one died of liver metastasis. Conclusion: Pneumococcal disease is a familial disease that can be cancerous and can be complicated by malignant tumors in other organs. It should be monitored for life. The treatment of choice for gastroscopy, colonoscopy resection, surgery to seek simplicity, to create conditions for follow-up after surgery.