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[目的]观察辨证分型联合西药治疗急性肾炎疗效。[方法]使用随机平行对照方法,将60例住院患者按随机数字表法分为两组。对照组30例双氢克尿噻,1~2mg/kg,3次/d,口服。氨苯蝶啶片1~2mg/kg+10%葡萄糖10mL,4~6次/d,静注;高血压加硝苯吡啶,0.1~0.2mg/kg,2~3次/d,口服。治疗组30例①风水相博,麻黄连翘赤小豆汤合五苓散(麻黄3~6g,连翘9g,赤小豆30g,五苓散5g)。②阴虚邪恋,知柏地黄丸合二至丸(知母、黄柏、桑白皮、黄芩、山楂、甘草各10g,生地15g,女贞子、旱莲草各20g,丹参30g),1剂/d,水煎100mL,早晚口服。西医治疗同对照组。连续治疗15d为1疗程。观测临床症状、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组痊愈22例,显效6例,有效1例,无效1例,总有效率96.67%。对照组痊愈15例,显效4例,有效1例,无效10例,总有效率66.67%。治疗组疗效优于对照组(P<0.05)。生化指标改善治疗组优于对照组(P<0.05)。[结论]辨证分型联合西药治疗急性肾炎效果显著,值得推广。
[Objective] To observe the effect of syndrome differentiation and western medicine in the treatment of acute nephritis. [Methods] Randomized parallel method was used to divide 60 inpatients into two groups according to random number table. Control group, 30 cases of hydrochlorothiazide, 1 ~ 2mg / kg, 3 times / d, orally. Triamterene tablet 1 ~ 2mg / kg + 10% glucose 10mL, 4 ~ 6 times / d, intravenous; Hypertension plus nifedipine, 0.1 ~ 0.2mg / kg, 2 to 3 times / d, orally. The treatment group of 30 cases ① Feng Shui phase Bo, Ephedra forsythia Chixiaodou soup combined Wulingsan (Ephedra 3 ~ 6g, forsythia 9g, red bean 30g, Wuling San 5g). ② Yin Xie Xie, cypress pill to two pills (Anemarrhena, Phellodendron, Morus alba, skullcap, hawthorn, licorice 10g, habitat 15g, Ligustrum lucidum, Eclipta 20g, Salvia 30g), 1 / d, decoction 100mL, morning and evening oral. Western medicine treatment with the control group. Continuous treatment of 15d for a course of treatment. Observed clinical symptoms, adverse reactions. Continuous treatment of 4 courses to determine the efficacy. [Result] In the treatment group, 22 cases were cured, 6 cases markedly effective, 1 effective and 1 ineffective, with a total effective rate of 96.67%. The control group cured 15 cases, 4 cases markedly effective in 1 case, ineffective in 10 cases, the total effective rate 66.67%. The treatment group was better than the control group (P <0.05). Biochemical index improved treatment group than the control group (P <0.05). [Conclusion] Syndrome differentiation and western medicine treatment of acute nephritis effect is significant, it is worth promoting.