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目的：观察经内镜胆管引流和联合应用中药治疗急性化脓性胆管炎（ＡＳＣ）的临床疗效及其对血清急性时相蛋白（ＡＰＰ）的影响。方法：将２６例ＡＳＣ患者随机分为内镜加中药组（Ａ组，１４例）和手术引流组（Ｂ组，１２例）。并监测治疗前后６种ＡＰＰ的变化。结果：２组患者入院时Ｃ反应蛋白（ＣＲＰ）、铜蓝蛋白（ＣＰ）、α１抗胰蛋白酶（α１ＡＴ）、α１酸性糖蛋白（α１ＡＧ）与正常参考值均出现显著增高，纤维连接蛋白（Ｆｎ）明显降低。Ａ组在治疗后第４日伴随Ｆｎ的上升，ＣＲＰ、ＣＰ、α１ＡＴ、α１ＡＧ均明显下降〔Ｆｎ：（０．２５±０．０４）ｇ／Ｌｖｓ．（０．１６±０．０８）ｇ／Ｌ；ＣＲＰ：（３０．１４±１６．７１）ｍｇ／Ｌｖｓ．（７６．４５±２６．３３）ｍｇ／Ｌ；ＣＰ：（０．６４±０．１５）ｇ／Ｌｖｓ．（０．９０±０．２１）ｇ／Ｌ；α１ＡＴ：（５．２９±０．９６）ｇ／Ｌｖｓ．（６．６３±１．５６）ｇ／Ｌ；α１ＡＧ：（０．９６±０．４４）ｇ／Ｌｖｓ．（１．７０±０．６１）ｇ／Ｌ，Ｐ＜０．０５或Ｐ＜０．０１〕。在治疗后第７日ＡＰＰ各项指标基本恢复至正常水平，且与Ｂ组比较有显著性差异（Ｐ＜０．０５或Ｐ＜０．０１）。结论：内镜与中药联合治疗Ａ?
Objective: To observe the clinical efficacy of endoscopic biliary drainage and combined Chinese medicine in the treatment of acute suppurative cholangitis (ASC) and its effect on serum acute phase protein (APP). Methods: Twenty-six patients with ASC were randomly divided into two groups: endoscopy plus traditional Chinese medicine (group A, n = 14) and surgical drainage (group B, n = 12). The changes of 6 kinds of APP before and after treatment were monitored. Results: The CRP, CP, α1 antitrypsin (α1AT) and α1AG in the two groups were significantly higher than those in the normal reference group. Fn )Obvious reduction. In group A, there was a significant decrease of CRP, CP, α1AT and α1AG with the increase of Fn on the fourth day after treatment [Fn: (0.25 ± 0.04) g / L vs. (0.16 ± 0.08) g / L; CRP: (30.14 ± 16.71) mg / Lvs. (76.45 ± 26.33) mg / L; CP: (0.64 ± 0.15) g / Lvs. (0.90 ± 0.21) g / L; α1AT: (5.29 ± 0.96) g / Lvs. (6.63 ± 1.56) g / L; α1AG: (0.96 ± 0.44) g / Lvs. (1.70 ± 0.61) g / L, P <0.05 or P <0.01〕. The index of APP returned to normal level on the 7th day after treatment and there was a significant difference (P <0.05 or P <0.01) compared with the B group. Conclusion: Endoscopic treatment with traditional Chinese medicine A?