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目的：研究蚊虫对拟除虫菊酯抗性的发生发展规律，深入探讨抗性机理。方法：在实验室条件下，对淡色库蚊敏感品系用二氯苯醚菊酯丙酮液筛选，连续筛选20代。结果：成功地选育出淡色库蚊实验室抗性品系，现抗性倍数保持在70倍左右。结论：该抗性品系的种群生存力明显降低，表现为用药后卵孵化率、化蛹率、羽化率和成成蚊率比正常的敏感品系要低。
Objective: To study the occurrence and development of pyrethroid resistance in mosquitoes and to explore the mechanism of resistance in depth. Methods: Under the laboratory conditions, sensitive strains of Culex pipiens pallens were screened with permethrin acetone solution and continuously selected for 20 generations. Results: The laboratory resistant strains of Culex pipiens pallens were successfully bred and the resistance multiple was kept at about 70 times. CONCLUSION: The population viability of this resistant strain was significantly reduced. The results showed that egg hatching rate, pupation rate, emergence rate and adult mosquito rate were lower than those of the normal susceptible strain.