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目的 了解糖尿病足感染细菌的分布及耐药状况.方法 收集2010年至2017年门诊和住院患者的糖尿病足感染标本,常规方法进行细菌培养和鉴定,按纸片法、微量稀释法或E-test法测定细菌药物敏感性.结果 共分离出非重复细菌304株,排在前4位的依次是金黄色葡萄球菌、铜绿假单胞菌、无乳链球菌和奇异变形杆菌,分别占29.3％,8.6％,5.9％,5.6％.未检出万古霉素耐药的革兰氏阳性细菌,未检出碳青霉烯类耐药的革兰氏阴性细菌.结论 糖尿病足感染的主要致病菌仍以金黄色葡萄球菌为主.“,”Objective To investigate the bacterial distribution and resistance to antibiotic in diabetic foot infection (DFI).Methods All the stains of outpatients and inpatients were isolated from infectious tissue in 2010-2017.The stains were cultured and identified by conventional method,and their susceptibility were tested by disk diffusion,microbroth dilution or E-test according to Clinical and Laboratory Standard Institute (CLSI,2015) manual.Results A total of 304 strains were collected.The four main species were Staphylococcus aureus,Pseudomonas aeruginosa,Streptococcus agalactiae,and Proteus mirabilis,accounting for 29.3％,8.6％,5.9％ and 5.6％ respectively.There was no resistance to vancomycin for gram-positive bacteria,and no resistance to carbapenem for gram-nagetive bacteria.Conclusion Staphylococcus aureus was predominant organism in DFI.