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虽然小肠占胃肠道长度的75％,但小肠肿瘤仅占所有胃肠肿瘤的3～6％,占全部胃肠道恶性肿瘤的1％。小肠肿瘤发病率低可能与碱性肠内容物及通过较快、细菌数量少、高浓度的IgA和肠内苯并芘羟化酶的高水平等保获性生理机制有关。作者回顾性研究了Vanderbilt大学医院1950～1978年临床诊断的92例原发性小肠肿瘤,不包括炎症和乏特氏壶腹或回盲瓣的肿瘤,其中良性22例(24％),
Although the small intestine accounts for 75% of the length of the gastrointestinal tract, small intestine tumors account for only 3 to 6% of all gastrointestinal tumors and 1% of all gastrointestinal cancers. The low incidence of small intestine tumours may be related to the physiological mechanisms of basic intestinal contents and high levels of retention, such as rapid, low bacterial counts, high concentrations of IgA, and high intestinal benzoquinone hydroxylase levels. The authors retrospectively studied 92 cases of primary small bowel tumors clinically diagnosed at the Vanderbilt University Hospital from 1950 to 1978. They did not include inflammatory and tumors of the ampulla of Vater or ileocecal valve, of which 22 cases were benign (24%).