各种植物病害严重危及全球粮食安全。植物进化出一系列防御反应机制来应对病原菌的威胁。泛素化是调控蛋白质的活性和稳定性一种重要的翻译后修饰方式。近十年来,人们越来越认识到泛素-26S蛋白酶体系统(UPS)在植物-病原菌互作中的重要调控作用。UPS在植物免疫的各个环节都发挥作用。UPS成为病原菌作用的靶标,要么抑制植物防卫反应,要么为病原菌自身服务。本文对UPS参与调控植物免疫的研究进展进行了简要的综述。 Various plant diseases seriously threaten global food security. Plants evolved a series of defense response mechanisms to deal with the threat of pathogens. Ubiquitination is an important post-translational modification that regulates the activity and stability of proteins. In the last decade, there is a growing recognition of the important regulatory role of the ubiquitin-26S proteasome system (UPS) in plant-pathogen interactions. UPS plays a role in every aspect of plant immunity. UPS acts as a target for pathogenic bacteria, either inhibiting plant defense response or serving the pathogen itself. This article summarizes the research progress of UPS involved in the regulation of plant immunity.