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目的 研究血清透明质酸 (Hyaluronic Acid,HA)、层粘蛋白 (L aminin,L N)对肿瘤的诊断价值。方法 采用放射免疫法测定 6 7例恶性肿瘤、16例良性肿瘤、2 1例正常对照者。数据均用 x± s表示 ,以正常人 x+ s作为上限计算阳性率。结果 恶性肿瘤患者的 HA、L N含量增多显著高于正常对照组及良性肿瘤 (P<0 .0 1) ,正常对照组与良性肿瘤间没有明显差异 (P>0 .0 5 )。结论 HA和 L N是较好的指标 ,有助于诊断肿瘤。
Objective To study the diagnostic value of serum hyaluronic acid (HA) and laminin (LN) for tumors. Methods Sixty-seven malignant tumors, 16 benign tumors and 21 normal controls were measured by radioimmunoassay. The data were expressed as x±s, and the positive rate was calculated using the normal x+s as the upper limit. Results The levels of HA and LN in patients with malignant tumors were significantly higher than those in normal controls and benign tumors (P < 0.01). There was no significant difference between normal controls and benign tumors (P> 0.05). Conclusions HA and LN are good indicators to help diagnose tumors.