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ＡＩＭＴｏｅｌｕｃｉｄａｔｅｔｈｅｂｉｏｌｏｇｉｃａｌａｎｄｃｌｉｎｉｃａｌｓｉｇｎｉｆｉｃａｎｃｅｏｆｓＩＣＡＭ１ａｎｄｓＶＣＡＭ１ｉｎｐａｔｉｅｎｔｓｗｉｔｈｇａｓｔｒｉｃｃａｎｃｅｒ．ＭＥＴＨＯＤＳＴｈｅｓｅｒｕｍｌｅｖｅｌｓｏｆｓｏｌｕｂｌｅＩＣＡＭ１ａｎｄＶＣＡＭ１ｗｅｒｅｍｅａｓｕｒｅｄｗｉｔｈｓａｎｄｗｉｔｈｅｎｚｙｍｅｉｍｍｕｎｏａｓｓａｙ．ＲＥＳＵＬＴＳＩｎｇａｓｔｒｉｃｃａｎｃｅｒｐａｔｉｅｎｔｓ，ｓｏｌｕｂｌｅＩＣＡＭ１ａｎｄＶＣＡＭ１ｃｏｎｃｅｎｔｒａｔｉｏｎｓｗｅｒｅｓｉｇｎｉｆｉｃａｎｔｌｙｅｌｅｖａｔｅｄｉｎｃｏｍｐａｒｉｓｉｏｎｗｉｔｈｔｈｏｓｅｏｆｈｅａｌｔｈｙｓｕｂｊｅｃｔｓ（２８９２３μｇ／Ｌ±３２６９μｇ／Ｌｖｓ１９０４４μ／Ｌ±３５９２μｇ／Ｌ，１４３０８８μｇ／Ｌ±４２１７１μｇ／Ｌｖｓ７２７２４μｇ／Ｌ±１５７６８μｇ／Ｌ，ｒｅｓｐｅｃｔｉｖｅｌｙ，Ｐ＜００１）．ＴｈｅｉｎｃｒｅｍｅｎｔｉｎｓｅｒｕｍｓＩＣＡＭ１ａｎｄｓＶＣＡＭ１ｃｏｎｃｅｎｔｒａｔｉｏｎｓｃｏｒｒｅｌａｔｅｄｗｅｌｗｉｔｈｔｈｅｓｔａｇｉｎｇｏｆｇａｓｔｒｉｃ?
AIMToelucidatethebiologicalandclinicalsignificanceofsICAM 1andsVCAM 1inpatientswithgastriccancer. METHODSTheserumlevelsofsolubleICAM 1 andVCAM 1weremeasuredwithsandwithenzymeimmunoassay. RESULTSIngineastriccancerpatients, solubleICAM-1andVCAM-1concentrationsweresignificantlyelevatedincomparisionwiththoseofhealthysubjects (28923μg / L ± 3269μg / Lvs19044μ / L ± 3592μg / L, 143088μg / L ± 42171μg / Lvs72724μg / L ± 15768μg / L, respectively, P <001). TheincrementinserumsICAM 1andsVCAM 1concentrationscorrelatedwelwiththestagingofgastric?