论文部分内容阅读
目的：为进一步探讨中药诱导细菌Ｌ型及其临床意义。方法：用大黄、黄连、丹参、板蓝根生药制成１０％煎剂。经药敏试验（Ｋ－Ｂ纸片法）与筛选，尔后再以不同浓度稀释经纸片法诱导金葡菌、痢疾杆菌、大肠杆菌形成Ｌ型。结果：经药敏试验筛选，三种中药浓度均在４０ｍｇ／片和５０ｍｇ／片诱导Ｌ型菌落及形态较典型。结论：大黄、黄连、丹参可使痢疾杆菌、大肠杆菌形成Ｌ型，提示临床用中药治疗急、慢性感染无效时，也要注意检查是否细菌变为Ｌ型及必要时调整用药，以免造成疾病迁延与再发。
Objective: To further explore the L type of bacteria induced by traditional Chinese medicine and its clinical significance. Methods: rhubarb, Coptis, Salvia, Radix is made of 10% decoction. The drug-sensitive test (K-B disc method) and screening, and then diluted with different concentrations by the paper-induced Staphylococcus aureus, Shigella, Escherichia coli L-form. Results: The results of drug susceptibility test screening, the concentration of three kinds of Chinese medicine in the 40mg / tablet and 50mg / tablet induced L-shaped colonies and more typical. Conclusion: Rhubarb, berberine and Salvia can cause Shigella dysentery and Escherichia coli to form L type. It is suggested that when clinical medicine is used to treat acute and chronic infections, it should be checked whether the bacteria become L type and medication is adjusted if necessary so as to avoid disease prolongation With the recurrence.