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目的:介绍酒精所致的内分泌障碍及酒精性肝病(ALD)的机制及治疗进展。方法:对近年文献进行复习。结果:本文对酒精对内分泌系统的影响及所致的功能障碍(尤其是对HPA轴、HPT轴及性腺轴的影响)的机制、治疗的进展,酒精性肝病的发生机制、分类及治疗进展进行了介绍。结论:酒精可导致内分泌系统功能障碍及肝功能障碍,酒精引起的障碍早期或可通过戒酒逆转,但晚期病变(如肝硬化)则很难逆转。对晚期患者,除戒酒之外,支持治疗是主要的手段。
Objective: To introduce the mechanism of endocrine disorders caused by alcohol and alcoholic liver disease (ALD) and its treatment progress. Methods: review the literature in recent years. Results: The mechanism of alcohol on the endocrine system and the resulting dysfunction (especially on the HPA axis, HPT axis and gonadal axis), the progress of treatment, the mechanism of alcoholic liver disease, classification and treatment progress Introduced. Conclusion: Alcohol can cause endocrine system dysfunction and liver dysfunction. Alcohol-induced disorder may be reversed early in alcohol abuse, but advanced disease (such as cirrhosis) is difficult to reverse. For advanced patients, in addition to alcohol, supportive treatment is the main means.