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目的：为探讨非洛地平缓释片（波依定）对高血压左心室肥厚的影响，将132例原发性高血压并发左心室肥厚的患者随机分为2组，治疗组68例，给予非洛地平缓释片口服；对照组64例，给予复方降压片治疗。疗程均为24周。两组均于用药前及服药24周后进行超声心动图检查，测量记录各种有关参数。结果：治疗组及对照组均有良好的降压作用，而治疗组对左室后壁厚度、空间隔厚度和左室重量指数有较好的降低作用（P＜0.05），对照组则无明显变化（P＞0.05），经24周的观察，未发现波依定有明显的毒副作用。结论：波依定是降压、逆转安室肥厚的有效药物。
OBJECTIVE: To investigate the effect of sustained-release tablets of felodipine on the left ventricular hypertrophy in hypertensive patients, 132 patients with essential hypertension complicated with left ventricular hypertrophy were randomly divided into two groups, 68 cases in the treatment group, Felodipine extended release tablets oral; control group of 64 cases, given compound antihypertensive tablets. The course of treatment was 24 weeks. Echocardiography was performed in both groups before treatment and 24 weeks after taking the drug. Various parameters were measured and recorded. Results: The treatment group and the control group had a good antihypertensive effect, while the treatment group had a good reduction of left ventricular posterior wall thickness, thickness of septum and left ventricular mass index (P <0.05), while the control group had no significant Changes (P> 0.05), after 24 weeks of observation, no obvious side effects of beidetin. Conclusion: Bo Yi Ding is an effective antihypertensive antihypertensive drugs.