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美《生命科学》第25卷(1979年5月24日)第227页报道:已发表的许多观察报告证明,恶性变细胞的胞核与相对的非恶性变细胞胞核相比,胞核出现异常,表现为:胞核大小及形状发生改变,胞核成分改变,胞核的生物合成活性增加。此外,据最近对人与动物恶性细胞的免疫细胞学研究,恶性细胞核含有可被抗瘤细胞核抗体检出的抗原。
US Life Science Volume 25 (May 24, 1979) page 227 Report: Many published reports have demonstrated that the nuclei of malignant cells appear as compared to the nuclei of relatively non-malignant cells Abnormalities, manifested as: changes in the size and shape of the nucleus, changes in the composition of the nucleus, increased nuclear biosynthesis activity. In addition, according to recent immunocytology studies on human and animal malignant cells, the malignant nuclei contain antigens detectable by anti-tumor cell nuclear antibodies.