本文报告6例小儿多发性硬化,发病年龄为5～13岁。首发症状3例为视力减退,2例为截瘫,1例为癫痫大发作。损害部位以视神经和脊髓为最多(100%和83%),癫痫发作次之(50%),小脑和脑干损害较少(各为33%)。复发4例(66.6%),停药太早和维持量太小是复发的原因。对类固醇疗法有良好反应,长期随访完全缓解3例(50%)。小儿预后可能较成人为佳。 This article reports 6 cases of children with multiple sclerosis, the age of onset of 5 to 13 years old. The first symptom of 3 cases of vision loss, 2 cases of paraplegia, 1 case of epileptic seizures. The lesions were mostly optic nerve and spinal cord (100% and 83%), followed by seizures (50%), with less cerebellar and brainstem damage (33% each). Recurrent in 4 cases (66.6%), withdrawal is too early and maintenance is too small is the reason for the recurrence. Good response to steroid therapy, long-term follow-up complete remission in 3 cases (50%). Pediatric prognosis may be better than adults.