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目的分析HIV/AIDS患者外周血T辅助细胞(CD4+)、T抑制细胞(CD8+)和白细胞(WBC)检测结果。方法 CD4+和CD8+计数通过免疫荧光标记,采用流式细胞仪检测;白细胞(WBC)计数采用全自动细胞分析仪检测。结果 118例HIV/AIDS住院患者,WBC降低组(3.00±0.61)×109/L的CD4+和CD8+分别为(68.60±38.98)个/ul和(266.89±126.52)个/ul,WBC正常组(7.13±5.12)×109/L的CD4+和CD8+分别为(104.39±61.37)个/ul和(380.17±134.06)个/ul,两者差异有统计学意义(t1=5.78t,2=3.62t,3=5.35,P均<0.01);两组别CD4+/CD8+比值比较均呈有统计学意义(P<0.05)。结论 HIV/AIDS患者在发病过程中与CD4+、CD4+/CD8+、WBC有密切相关,建议HIV感染者尽早进行医学咨询并做CD4+、CD8+和血常规的检测,以了解病情的进展及进行抗病毒治疗。
Objective To analyze the detection results of peripheral blood T helper cells (CD4 +), T suppressor cells (CD8 +) and white blood cells (WBC) in HIV / AIDS patients. Methods The counts of CD4 + and CD8 + were detected by immunofluorescence and flow cytometry. WBC count was detected by automatic cell analyzer. Results Among 118 HIV / AIDS hospitalized patients, the WBC reduction group (3.00 ± 0.61) × 109 / L had (68.60 ± 38.98) / ul and (266.89 ± 126.52) / ul CD4 + and CD8 + (104.39 ± 61.37) / ul and (380.17 ± 134.06) / ul respectively, with significant difference between the two groups (t = 5.78t, 2 = 3.62t, 3 = 5.35, P <0.01). The ratio of CD4 + / CD8 + between the two groups showed statistical significance (P <0.05). Conclusion HIV / AIDS patients are closely related to CD4 +, CD4 + / CD8 + and WBC in the process of onset. It is suggested that HIV-infected patients should get medical consultation as soon as possible and do CD4 +, CD8 + and blood tests to understand the progress of the disease and to conduct antiviral therapy .