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三效青霉素是上海第三制药厂根据国外同类产品进行配方试制的新制剂,其中含有苄星青霉素、普鲁卡因青霉素G、青霉素钾盐及少量稳定剂。为了消除在临床使用苄星青霉素(120万单位)肌肉注射时所产生的疼痛和堵针现象,该厂在苄星青霉素原料工艺上作了改进,并试制了三效青霉素新制剂。经上海华山医院等六个单位进行了临床试用,并对三效青霉素进行了如下有关临床药理考察。
Three-effect penicillin is the third pharmaceutical company in Shanghai according to the formulation of similar foreign products trial preparation of the new preparation, which contains benzathine penicillin, procaine penicillin G, penicillin potassium and a small amount of stabilizer. In order to eliminate the pain and plugging phenomenon caused by intramuscular injection of benzathine penicillin (1.2 million units) in clinical practice, the factory made improvements on the process of raw materials of benzathine penicillin and trial-produced a new three-effect penicillin preparation. The Shanghai Huashan Hospital and other six units for clinical trial, and penicillin three for the following clinical and pharmacological investigations.