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目的 研究早期自体角膜缘移植对碱烧伤后角膜血管新生 (CNV)的影响。方法 2 0只家兔 ,用NaOH建立角膜新生血管动物模型。在伤后 1、3、5、7天进行自体角膜缘移植。结果 角膜上皮愈合时间手术组平均 12 3 8天 ,对照组 19天。CNV程度 :手术组 1～ 2级 15眼占 93 75 % ,对照组 3～ 4级 4眼占 10 0 %。手术组CNV侵入角膜少 ,血管细小 ,管腔内红细胞少。结论 自体角膜缘移植可抑制CNV ,促进角膜上皮的愈合。
Objective To investigate the effect of early corneal limbal autograft on corneal neovascularization (CNV) after alkali burn. Methods Twenty rabbits were established corneal neovascularization animal model by NaOH. On the 1st, 3rd, 5th and 7th day after injury, limbal autografts were performed. Results Corneal epithelial healing time was 12 38 days in the operation group and 19 days in the control group. The degree of CNV was 15 75% in operation group 1 ~ 2 and 93% in 4 ~ 4 cases in control group, and 10% in control group. CNV invasion corneal surgery less small blood vessels, small red blood cells within the lumen. Conclusion Autologous limbal transplantation can inhibit CNV and promote the healing of corneal epithelium.