肺癌脑转移的发生率较高，是肺癌治疗失败的常见原因。对脑转移合并其他部位转移或肺原发灶未控制者，以化疗为主，一般选择能通过血脑屏障的药物，但疗效不尽理想。如何使常规化疗药物透过血脑屏障，已越来越引起临床医生的关注。现对我院1997年至1998年收治的31例肺癌伴脑转 The high incidence of brain metastases in lung cancer is a common cause of lung cancer treatment failure. For brain metastases with other metastatic sites or uncontrolled primary lung lesions, chemotherapy is the main method, and drugs that can pass through the blood-brain barrier are generally selected, but the efficacy is not ideal. How to make conventional chemotherapeutic drugs penetrate the blood-brain barrier has drawn more and more attention from clinicians. 31 cases of lung cancer with brain transfer admitted to our hospital from 1997 to 1998