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应用放射免疫法检测72例肝病患者的空腹血清胃泌素含量。结果表明急性肝炎组、慢性肝炎组血清胃泌素含量正常。肝硬化患者常有高胃泌素血症,有显著门脉高压的失代偿肝硬化患者血清胃泌素升高更显著。高胃泌素血症与门脉高压性胃粘膜病变引起的上消化道出血密切相关。血清胃泌素的测定对预测出血有一定价值。
Fasting serum gastrin levels in 72 patients with liver disease were detected by radioimmunoassay. The results showed that acute hepatitis group, chronic hepatitis group serum gastrin normal. Patients with liver cirrhosis often have hypergastrinemia, elevated serum gastrin in patients with decompensated cirrhosis who have significant portal hypertension is more pronounced. Hypergastrinmia is closely related to upper gastrointestinal bleeding caused by portal hypertensive gastric mucosal lesions. Determination of serum gastrin has a certain value in predicting bleeding.