论文部分内容阅读
目的探讨分化型甲状腺癌(DTC)术后,18F-FDGPET/CT在甲状腺癌复发及转移中的应用。方法 36例DTC术后合并131I治疗患者,分别行18FDGPET/CT全身显像及131I全身扫描(131I-WBS),同时检测患者血清甲状腺球蛋白(Tg)。结果 34例Tg阳性的患者中131I-WBS10例阳性,PET/CT显像19例阳性。2例Tg阴性的患者中131I-WBS和PET/CT显像均阴性。3例在131I-WBS中提示甲状腺肿瘤残存者,在PET/CT检查中均为阳性;7例在131I-WBS中提示淋巴结转移者,在PET/CT检查中均为阳性,在131I-WBS阴性患者中PET/CT显像发现6例肺转移患者及3例骨转移。结论 PET/CT和131I扫描在甲状腺残存及淋巴结转移的诊断中,两种检查大致相同,但PET/CT比131I扫描在诊断骨转移及肺转移中更具有优势,另外,PET/CT在Tg升高而131I-WBS阴性的病人中应用有很重要的意义。PET/CT尚可发现其他良性及恶性病变,在DTC的再分期中有重要价值。
Objective To investigate the application of 18F-FDG PET / CT in the recurrence and metastasis of thyroid carcinoma after differentiated thyroid cancer (DTC). Methods Thirty-six patients with DTC and 131I were enrolled in the study. 18FDGPET / CT whole body imaging and 131I whole body scanning (131I-WBS) were performed respectively. Serum thyroglobulin (Tg) was also detected. Results Among the 34 cases with Tg positive, 10 cases of 131I-WBS were positive and 19 cases of PET / CT were positive. Two cases of Tg negative in patients with 131I-WBS and PET / CT imaging were negative. The remaining 131I-WBS showed remnant in thyroid tumor, which was positive in PET / CT examination. Seven of the 131I-WBS patients with lymph node metastasis were positive in PET / CT examination and 131I-WBS negative Six cases of lung metastases and three cases of bone metastases were found in PET / CT imaging. Conclusions Both PET / CT scan and 131I scan have similar advantages in the diagnosis of thyroid remnant and lymph node metastasis, but PET / CT is more advantageous than 131I scan in the diagnosis of bone metastasis and lung metastasis. In addition, High and 131I-WBS-negative patients in the application of great significance. PET / CT can still be found in other benign and malignant lesions, DTC in the re-stage has important value.