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1病历资料患者,女,48岁,主因间断乏力4年入院。此前曾在外院住院化验全血细胞减少,多次骨穿示骨髓浆细胞增多但均在10%以下且为成熟浆细胞,化验免疫球蛋白IgA4.42g/l、IgG16.2g/l略增高,血蛋白电泳示轻链K轻链增高为378mg/dl,λ轻链增高为215mg/dl,全身ECT无异常,先后予大剂量丙球,环孢素及强的松、马兰+强的松、反应停+地塞米松化疗多次,病情无好转且逐渐加重来我院。入院检查:贫血貌,皮肤粘膜无出血点、瘀斑,浅表淋巴结
A patient data, female, 48 years old, mainly due to intermittent weakness 4 years admitted to hospital. Had previously hospitalized in the outer hospital pancytopenia, repeated bone showed bone marrow plasma cells increased but were below 10% and mature plasma cells, laboratory immunoglobulin IgA4.42g / l, IgG16.2g / l slightly increased, blood Protein electrophoresis showed that the light chain K light chain increased to 378mg / dl, λ light chain increased to 215mg / dl, systemic ECT no abnormalities, successively to large doses of ciliary, ciclosporin and prednisone, Malan + prednisone, reaction Stop + dexamethasone chemotherapy several times, no improvement in the condition and gradually increased to our hospital. Admission examination: anemia appearance, skin and mucous membrane without bleeding, ecchymosis, superficial lymph nodes