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目的了解本市肺炎支原体(MP)感染发病情况及临床特点,为预防和诊治MP感染提供参考。方法对2000~2005年我院收治的呼吸道感染患儿进行肺炎支原体抗体(MP-IgM)检测,并对703例阳性病例资料进行回顾性分析。结果MP感染患儿占呼吸道感染的22.06%,近年来呈增长趋势,发病年龄逐年提前,冬春季节儿童呼吸道支原体感染多发,临床表现以发热、咳嗽最为常见,常可累及心、肝、肾、胃肠道等肺外器官,红霉素+阿奇霉素序贯疗法治愈率为100%。结论MP是儿童时期呼吸道感染的重要病原体之一,婴幼儿及学龄前儿童为高危人群,MP-IgM检测结合临床可确诊,红霉素+阿奇霉素序贯疗法效果最佳。
Objective To understand the incidence and clinical features of Mycoplasma pneumoniae (MP) infection in our city and provide references for the prevention and treatment of MP infection. Methods Mycoplasma pneumoniae antibody (MP-IgM) was detected in children with respiratory tract infection admitted to our hospital from 2000 to 2005. The data of 703 positive cases were analyzed retrospectively. Results The children with MP infection accounted for 22.06% of the total number of respiratory infections in recent years. The incidence of this disease was increasing year by year. In winter and spring, children with Mycoplasma pneumoniae infection were more frequent. The clinical manifestations were fever and cough, Extraintestinal organs such as the gastrointestinal tract, erythromycin + azithromycin sequential therapy cure rate was 100%. Conclusion MP is one of the most important pathogens in childhood respiratory tract infection. Infants and preschool children are at high risk. MP-IgM combined with clinically diagnosed MP is the best, and sequential therapy with erythromycin and azithromycin is the best.