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目的验证平阳霉素局部注射治疗血管瘤特别是颜面部血管瘤的疗效。方法将平阳霉素 8mg加生理盐水 3～ 5ml溶解后行血管瘤 ( 0 .5× 1.0cm2 ～ 4.0× 5 .0cm2 )内注射至局部肿胀、苍白。若血管瘤面积较大或多发时 ,一次注药未愈者 ,可分次、分点注药 ,每次间隔 1～ 2周 ,直至治愈为止。共治疗 60 8例 ,一般用药总量不超过40mg。结果经 1次注射治愈 3 0 2例 ,2～ 3次注射治愈 2 66例 ,面积最大或多发血管瘤分别经7～ 8次注药后治愈。经 1～ 4年随访 ,总有效率为 95 .1%。结论本方法具有操作简单、疗效显著、并发症少等优点 ,只要使用方法正确 ,治疗后不留畸形 ,特别适于体表中小面积血管瘤的治疗。
Objective To verify the efficacy of local injection of Pingyangmycin in the treatment of hemangiomas, especially facial hemangiomas. Method Pingyangmycin 8mg plus normal saline 3~5ml dissolved in hemangiomas (0.5×1.0cm2~4.0×5.0cm2) to local swelling and pale. If the area of hemangioma is large or multiple, one-time injection of untreated patients may be divided into sub-points and injections at intervals of one to two weeks at a time until it is cured. A total of 60 8 cases were treated, and the total amount of general medication does not exceed 40 mg. Results After one injection, 322 patients were cured, 2～3 injections were used to cure 2 66 patients, and the area or hemangiomas were cured after 7-8 injections. After 1 to 4 years of follow-up, the total effective rate was 95.1%. Conclusion: This method has the advantages of simple operation, significant efficacy, and few complications. It is suitable for the treatment of small and medium-sized hemangiomas on the surface as long as the method is correct and no abnormalities remain after treatment.