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目的探讨乳酸脱氢酶(LDH)在恙虫病患者中的临床意义。方法回顾性分析35例恙虫病患者(恙虫病组)的临床资料,另选取35例同期健康体检者作为对照组,检测血清LDH水平,分析恙虫病患者LDH与ALT、AST及D-二聚体的相关性。结果恙虫病组LDH水平均升高,其值为(455.9±163.6)U/L,高于对照组的(178.0±27.7)U/L(P<0.01)。恙虫病患者LDH与ALT(r=0.639,P<0.01)、AST(r=0.696,P<0.01)及D-二聚体(r=0.709,P<0.01)呈正相关。结论恙虫病患者血清LDH升高,可作为早期诊断及评估疾病严重程度的良好指标。
Objective To investigate the clinical significance of lactate dehydrogenase (LDH) in patients with scrub typhus. Methods The clinical data of 35 patients with scrub typhus (scrub typhus) were retrospectively analyzed. Another 35 healthy subjects were selected as the control group. Serum LDH levels were measured. The levels of LDH, ALT, AST and D-dimer in patients with scrub typhus Relevance. Results The levels of LDH in scrub typhus group were all higher than those in control group (455.9 ± 163.6 U / L, 178.0 ± 27.7 U / L, P <0.01). LDH was positively correlated with ALT (r = 0.639, P <0.01), AST (r = 0.696, P <0.01) and D-dimer (r = 0.709, P <0.01) Conclusions Serum LDH is elevated in patients with scrub typhus and can be used as a good indicator for early diagnosis and assessment of the severity of the disease.