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目的探讨影响北京市普通人群血清甲型H1N1流感病毒抗体阳性的因素。方法按1∶1配对的病例对照研究设计,采用问卷调查方法,收集65例血清甲型H1N1流感病毒抗体阳性病例和65例阴性对照者的人口统计学特征、疫苗接种史,卫生习惯等信息。结果单因素分析显示,疫苗接种史、旅游史、调查前曾出现流感样症状、周围有确诊的甲型H1N1流感患者、调查前曾去医院发热门诊、勤洗手习惯等与血清甲型H1N1流感病毒抗体阳性有关。多因素条件Logistic回归分析结果表明,甲型H1N1流感病毒疫苗接种史(OR=4.82,95%CI:1.23~19.91)、调查前1月内曾出现过流感样症状(OR=2.53,95%CI:1.01~6.25),勤洗手习惯(OR=0.21,95%CI:0.06~0.74)等3个因素与血清甲型H1N1流感病毒抗体阳性有关。结论甲型H1N1流感疫苗接种史、旅游史、曾出现流感样症状、曾与确诊的甲型H1N1流感患者接触、勤洗手习惯等与血清甲型H1N1流感病毒抗体阳性有关。提示应当继续推行甲型H1N1流感疫苗的接种,加强手卫生等一般措施是预防甲型H1N1流感的重要手段。
Objective To explore the factors influencing the positive rate of serum A (H1N1) virus in the general population in Beijing. Methods A case-control study was designed according to a 1: 1 pairing. The questionnaires were used to collect demographic characteristics, vaccination history and hygiene habits of 65 cases of positive cases of influenza A (H1N1) virus and 65 cases of negative controls. Results Univariate analysis showed that flu-like symptoms were found in the history of vaccination, travel history and investigation, there were confirmed cases of Influenza A (H1N1) influenza in the hospital before the survey, Antibody positive. Logistic regression analysis showed that influenza A (H1N1) virus vaccination history (OR = 4.82, 95% CI: 1.23-19.91) had flu-like symptoms within one month before the survey (OR = 2.53, 95% CI : 1.01 ~ 6.25). The three factors of washing habit (OR = 0.21, 95% CI: 0.06 ~ 0.74) were related to the positive of serum A (H1N1) Conclusions Influenza A (H1N1) virus vaccination history and tourism history have shown flu-like symptoms. It has been associated with the confirmed H1N1 influenza patients and frequent washing habits. It is suggested that the vaccination of influenza A (H1N1) should be continued and the general measures such as hand hygiene should be strengthened to prevent Influenza A (H1N1).