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目的:研究基底动脉尖综合征(Top of the basilar arterysy ndrome,TOBS)的病因、临床表现和影像学表现,加深对这种疾病的认识。方法:我们对自2005年以来收治的6例TOBS患者的原始资料进行回顾性分析。结果:栓塞可能是TOBS的主要病因之一,高危因素有高血压、糖尿病、心脏病、高血脂等,临床表现多以突然眩晕或意识障碍起病,合并眼球运动障碍及瞳孔异常、运动障碍、偏盲,可伴有行为异常等。CT及MRI提示重要的特征是中脑或丘脑梗死合并其他部位梗死,如枕叶、小脑、颞叶。结论:TOBS的诊断主要依赖临床及影像学表现,早期全面综合治疗可以提高生存率。
Objective: To study the etiology, clinical manifestations and imaging manifestations of Top of the basilar arterysyndrome (TOBS) and to deepen the understanding of this disease. METHODS: We retrospectively analyzed the original data of 6 TOBS patients who were treated since 2005. Results: Embolism may be one of the major causes of TOBS. High risk factors include hypertension, diabetes, heart disease, hyperlipidemia, clinical manifestations and more sudden onset of vertigo or disturbance of consciousness, eye movement disorders and pupil abnormalities, dyskinesia, Hemianopia, may be associated with abnormal behavior. CT and MRI suggest an important feature is the infarction in the middle cerebral or thalamic infarction and other parts of the infarct, such as occipital lobe, cerebellum, temporal lobe. Conclusion: The diagnosis of TOBS mainly depends on the clinical and imaging findings. Early comprehensive and comprehensive treatment can improve the survival rate.