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目的对农村牙周炎的发病情况及与冠心病的相关性进行探讨研究。方法将200例研究对象根据身体健康状况进行分为4组,分别对每组研究对象进行牙周临床指数的检查、血浆纤维蛋白原(Fg)质量浓度与冠心病常规血清学指标的测定。结果牙周炎患者患冠心病的可能性升高,约为口腔健康者的2.531倍(P=0.049);4组研究对象的血浆Fg质量浓度分别为(2.38±0.25)g/L、(3.61±0.67)g/L、(4.07±0.81)g/L和(4.1 2±0.82)g/L,牙周炎患者(牙周炎组和牙周炎+冠心病组)的血浆Fg质量浓度明显高于健康对照组,差异有统计学意义(P<0.05);此外,冠心病患者(冠心病组和牙周炎+冠心病组)的低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)和甘油三酯(TG)的含量水平均高于健康者和牙周炎组患者,且差异均有统计学意义(P<0.05)。结论农村牙周炎与冠心病间存在一定的相关性,两者可相互影响。
Objective To investigate the incidence of periodontitis in rural areas and its relationship with coronary heart disease. Methods 200 subjects were divided into 4 groups according to their health status. Periodontal clinical indexes, plasma fibrinogen (Fg) concentrations and routine serum markers of coronary heart disease were determined in each group. Results The incidence of coronary heart disease in patients with periodontitis was 2.531 times higher than that in oral health patients (P = 0.049). The plasma Fg concentrations in the four groups were (2.38 ± 0.25) g / L and ± 0.67) g / L, (4.07 ± 0.81) g / L and (4.1 2 ± 0.82) g / L, respectively. The plasma Fg concentrations in patients with periodontitis (periodontitis and periodontitis + coronary heart disease) (P <0.05). In addition, the levels of low density lipoprotein cholesterol (LDL-C) and total cholesterol (P <0.05) in patients with coronary heart disease and with periodontitis and coronary heart disease were significantly higher than those in healthy controls TC and triglyceride were higher than those in healthy and periodontitis groups (P <0.05). Conclusion There is a certain correlation between periodontitis and coronary heart disease in rural areas, and the two can affect each other.