急性脑梗死患者静脉溶栓后中医证候要素演变

来源 :北京中医药大学学报 | 被引量 : 0次 | 上传用户:passat168
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目的 研究急性脑梗死经静脉溶栓治疗的患者,其在发病14天内的证候要素分布和随时间的演变情况.方法 纳入脑梗死发病6 h内,经静脉重组组织型纤维蛋白酶原激活剂(rt-PA)溶栓的患者56例.分别在其发病的第1、3、5、7、14天采集中医证候要素信息.综合各项信息与数据,进行统计学处理分析.结果 在患者的证候要素演变中,第1天内风证占主导地位,其次血瘀证及痰湿证所占比例也较高,随着病程进展,内风证在第3天迅速降低,至第14天消失;痰湿证、血瘀证有下降趋势,但所占比例仍较高.随着时点推移,气虚证逐渐增多,在第7天成为最主要证候要素.内火证在第5天升高后又趋于初始比例,阴虚证所占比例始终较低,且随时间推移有下降趋势.结论 脑梗死超早期,患者证候要素以实证为主,其中以风证为主导,证候组合以风、痰、瘀之间的2个基本证候组合最多,其次是3个基本证候的组合.与既往研究脑梗死证候要素的演变规律结果相比较,本研究中患者在溶栓治疗后,其临床证候组合形式逐渐减少,且实证逐渐减少,气虚证更加突出.
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