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目的:探讨血管紧张素转换酶抑制剂(ACEI)捷赐瑞对高血压患者尿微量蛋白(Alb)的影响。方法:将120例高血压患者分为捷赐瑞组、氨氯地平组各60例,在6个月的治疗期前后,测定血压、血肌酐、尿素氮、尿酸及尿Alb、α1-微量球蛋白、IgG。结果:两组治疗前后血压均有较明显的下降(P<0.05),但Alb的下降,捷赐瑞组明显优于氨氯地平组。结论:ACEI可明显降低高血压患者的血压,保护肾功能,其作用优于氨氯地平。
Objective: To investigate the effect of angiotensin converting enzyme inhibitor (ACEI) Jie Ci Rui on urinary microalbumin (Alb) in patients with hypertension. Methods: A total of 120 hypertensive patients were divided into Jieserui group and amlodipine group, with 60 patients in each group. Blood pressure, serum creatinine, urea nitrogen, uric acid and urine Alb, α1-microglobulin Protein, IgG. Results: Before and after treatment, the blood pressure decreased obviously (P <0.05), but Alb decreased. Conclusion: ACEI can significantly reduce the blood pressure in patients with hypertension, renal function protection, its effect is superior to amlodipine.