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三十年代中期开始怀疑石棉引起支气管肺癌,但直至1968年才推测石棉与吸烟结合比单独作用致癌率高。因为吸烟与肺癌的关系已充分肯定,重要的是区别石棉相关肿瘤与吸烟相关肿瘤的标准。现一致认为,石棉相关肺癌的诊断需有石棉沉着病的存在作为肺实质石棉负荷的证据。尸检证明,肺内石棉纤维负荷定量也可为石棉接触提供客观证据。据此,作者用电子光学方法对75例男性肺癌的肺石棉纤维进行了定
In the mid-1930s, bronchial lung cancer was suspected to have been caused by asbestos, but it was not until 1968 that asbestos combined with smoking was more likely to cause cancer than alone. Because the relationship between smoking and lung cancer has been fully affirmed, it is important to distinguish between asbestos-related tumors and smoking-related tumors. It is now agreed that the diagnosis of asbestos-related lung cancer requires the presence of asbestosis as evidence of asbestos burden in the lung parenchyma. Autopsy has shown that quantification of asbestos fiber load in the lung can also provide objective evidence of asbestos exposure. Based on this, the authors used electronic optics to determine 75 cases of lung asbestos fibers in male lung cancer.