抗菌素在临床中应用常伴有多种并发症,包括过敏反应、毒性反应、耐药菌的扩展以及二重感染。在研究宿主抗感染的防御机理中,有认为二重感染的发生主要应归咎于宿主内在防御力的异常。例如,曾证明烧伤患者的嗜中性白细胞的功能发生周期性变异,且在嗜中性 The clinical use of antibiotics is often accompanied by a variety of complications, including anaphylaxis, toxic reactions, expansion of resistant bacteria, and double infection. In studying the defense mechanism of host anti-infective, it is considered that the occurrence of double infection should be mainly attributed to the host’s inherent defense abnormalities. For example, it has been demonstrated that neutrophils in burn patients undergo periodic variations in their function and that in neutrophils