用电化学方法研究了青蒿素与氯化血红素之间的相互作用.青蒿素在玻璃碳电极上于-1.08V处发生一个2电子转移的不可逆还原.但是,即使在低至4.0×10~(-8)mol/L氯化血红素存在下,青蒿素仍可被催化还原,阴极过电位降低了600mV.配合物EDTA-Fe(Ⅲ)具有类似氯化血红素的催化性质,它降低了QHS阴极过电位590mV.在这个体系中,青蒿素在碳电极上的还原是一个借助于氯化血红素催化的还原过程,氯化血红素的存在降低了青蒿素还原活化能,促进了青蒿素的分解.文中讨论了该反应的还原机理. The interaction between artemisin and hemin was studied electrochemically.An artemisinin produced an irreversible reduction of 2 electron transfer at -1.08 V on glassy carbon electrode.However, even at as low as 4.0 × Under the presence of 10 ~ (-8) mol / L hemin, artemisinin could still be catalytically reduced and the cathodic overpotential decreased by 600mV. The complex EDTA-Fe (Ⅲ) possessed the catalytic properties similar to that of hemin. It reduces the QHS cathodic potential by 590mV. In this system, the reduction of artemisinin at the carbon electrode is a reduction catalysed by means of hemin, which reduces the activation energy of artemisinin reduction , Promoted the decomposition of artemisinin.This paper discussed the reduction mechanism of the reaction.